Mitch Pileggi & Cara Buono Cast in Supergirl

Deadline is reporting that Cara Buono and Mitch Pileggi will recur on the upcoming season of Supergirl as Gamemnae and Rama Khan, respectively. The characters are described as follows,

Gamemnae, an ancient alien, who with others of her kind, have been safeguarding the Earth from the follies of humanity throughout the ages. Gamemnae’s aim is to use technology to subjegate humans. Gamemnae is cunning, witty, ruthless, and always ten steps ahead of her adversaries. Gamemnae’s agenda puts her into conflict with her would-be allies and on a collision course with Supergirl.

...Rama Khan, an ancient alien who is able to control the four ancient elements — fire, water, earth, and air. Arrogant and willful, Rama Khan has been entrusted to use his powers to protect the Earth from mankind for millions of years but now his agenda puts him at odds with Supergirl as well as Lena Luthor.